How did the winners of the Nobel Medicine Prize Tricks Cancer cells?
Japanese scientists, Tasuku Honjo and James B. Allison, won the 2018 Nobel Prize for Medicine for discovering the immune system’s anti-cancer brakes.
In the 1980s, the two worlds discovered two new parts of the human immune system. They did not expect to have anything to do with the development of malignancies in the human body.
It turned out that the two worlds had discovered two receptors that would benefit from the malignancy to deceive our immune system. By using them, T lymphocytes stop responding to cancer cells as aggressor cells, rather they consider them friendly cells.
It became clear to all after the discovery by the American and Japanese worlds what happens in the human body when the development of cancer in it. In fact, the two worlds have discovered a mechanism for controlling immunity, which is limited to preventing T lymphocytes from responding to the danger of responding to the appearance of malignancies.
The two scientists discovered that cancer cells send T-receptor receptors with signals that play the role of inhibitors, which are received by lymphocytes and considered not to attack cancer cells.
After the principle of the immune system was discovered in case of cancer, it is enough for scientists to devise artificial antibodies that replace T cells to receive deceptive signals from cancer cells. It was on this principle to develop drugs that fight cancer.
So far tens of thousands of patients have been immunized, allowing them to extend their lives or recover from cancer, although there are many side effects associated with the use of these effective drugs.